Protein profile

VK055_5023

hypothetical protein

Genome: KpATCC43816

Gene: AIK83549.1 Structure source: AlphaFold + ColabFold UniProt A0A088MRP9
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Amino acids 579
Annotations 0
Features 11
PDB binders 0
Druggability 0.688

Overview

Basic information about this protein and its source genome.

Accession
VK055_5023
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83549.1
Status
annotated
Amino acids
579
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
OuterMembrane
ColabFold pLDDT
82.77

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.688
Structure A0A088MRP9
Pocket Pocket 23
P2Rank 0.272
Structure A0A088MRP9
Pocket Pocket 1
ColabFold model
FPocket 0.461 · Pocket 2
P2Rank 0.167 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
100 408 Gene3D G3DSA:2.160.20.10 -
100 408 InterPro IPR012334 Pectin lyase fold
1 28 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 28 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
108 429 SUPERFAMILY SSF51126 Pectin lyase-like
108 429 InterPro IPR011050 Pectin lyase fold/virulence factor
29 579 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
14 24 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 28 Phobius SIGNAL_PEPTIDE Signal peptide region
25 28 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 13 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A088MRP9
AlphaFold — — full sequence — Viewing
ColabFold VK055_5023
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
23 0.688
34 0.576
3 0.004
17 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.44 0.272
2 3.84 0.121
3 2.72 0.066
4 1.43 0.015
5 1.36 0.014