Metabolic network

VK055_5038

phosphoribosyl-ATP diphosphatase

Back to protein
Network centrality 0.06154 top 96.2%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Histidine metabolism, no isoenzyme backup detected, more central than 96.2% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Histidine metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

HISTPRATPHYD-RXN

EC 3.6.1.31 · HISTPRATPHYD-RXN · not reversible · no isoenzyme backup

Producing chokepoint
1-(5-phospho-beta-D-ribosyl)-ATP H2O
→
1-(5-phospho-beta-D-ribosyl)-AMP diphosphate H+

Imported from KpATCC43816.sbml · 2026-07-09