KEGG:map00340

Histidine metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 17
Proteins 15
Metabolites 34
Chokepoints 7

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 13 shared KEGG Purine metabolism 7 shared KEGG Pentose phosphate pathway 2 shared KEGG Nicotinate and nicotinamide metabolism 2 shared KEGG Pyrimidine metabolism 2 shared KEGG Glutathione metabolism 1 shared KEGG Aminoacyl-tRNA biosynthesis 1 shared KEGG Phenylalanine, tyrosine and tryptophan biosynthesis 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

GLUTAMIDOTRANS-RXN

EC 4.3.2.10 · R04558 · GLUTAMIDOTRANS-RXN · not reversible

L-glutamine phosphoribulosylformimino-AICAR-phosphate
→
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide D-erythro-1-(imidazol-4-yl)-glycerol 3-phosphate L-glutamate H+
VK055_5039 VK055_5041

GLUTCYSLIG-RXN

EC 6.3.2.2 · R00894 · GLUTCYSLIG-RXN · not reversible

producing
L-cysteine L-glutamate ATP
→
gamma-L-glutamyl-L-cysteine ADP H+ phosphate
VK055_4497

HISTAMINOTRANS-RXN

EC 2.6.1.9 · R03243 · HISTAMINOTRANS-RXN · reversible

2-oxoglutarate L-histidinol phosphate
⇌
3-(imidazol-4-yl)-2-oxopropyl phosphate L-glutamate
VK055_5043

HISTCYCLOHYD-RXN

EC 3.5.4.19 · R04037 · HISTCYCLOHYD-RXN · not reversible

1-(5-phospho-beta-D-ribosyl)-AMP H2O
→
1-(5-phospho-beta-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
No mapped protein

HISTPRATPHYD-RXN

EC 3.6.1.31 · R04035 · HISTPRATPHYD-RXN · not reversible

producing
1-(5-phospho-beta-D-ribosyl)-ATP H2O
→
1-(5-phospho-beta-D-ribosyl)-AMP H+ diphosphate
VK055_5038

IMIDPHOSDEHYD-RXN

EC 4.2.1.19 · R03457 · IMIDPHOSDEHYD-RXN · not reversible

D-erythro-1-(imidazol-4-yl)-glycerol 3-phosphate
→
3-(imidazol-4-yl)-2-oxopropyl phosphate H2O
No mapped protein

PRIBFAICARPISOM-RXN

EC 5.3.1.16 · R04640 · PRIBFAICARPISOM-RXN · not reversible

both
1-(5-phospho-beta-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
→
phosphoribulosylformimino-AICAR-phosphate
VK055_5040

RXN-7587

EC - · R04282 · RXN-7587 · not reversible

4-imidazolone-5-propanoate H2O
→
formyl-L-isoglutamine
No mapped protein

RXN-7594

EC - · R00270 · RXN-7594 · not reversible

4-oxoglutaramate H2O
→
2-oxoglutarate ammonium
No mapped protein