Protein profile

VK055_5066

hypothetical protein

Genome: KpATCC43816

Gene: AIK83592.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVQ4
Export view
Amino acids 110
Annotations 0
Features 7
PDB binders 0
Druggability 0.513

Overview

Basic information about this protein and its source genome.

Accession
VK055_5066
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83592.1
Status
annotated
Amino acids
110
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
25.843
Localization
Unknown
ColabFold pLDDT
95.51

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.513
Structure A0A0H3GVQ4
Pocket Pocket 1
P2Rank 0.589
Structure A0A0H3GVQ4
Pocket Pocket 1
ColabFold model
FPocket 0.575 · Pocket 1
P2Rank 0.736 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 66 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
14 98 Pfam PF09313 Domain of unknown function (DUF1971)
14 98 InterPro IPR015392 Domain of unknown function DUF1971
4 108 SUPERFAMILY SSF51197 Clavaminate synthase-like
3 107 PIRSF PIRSF020632 YeaR
3 107 InterPro IPR014510 Tellurite resistance predicted, YeaR
3 109 Gene3D G3DSA:2.60.120.10 Jelly Rolls
3 109 InterPro IPR014710 RmlC-like jelly roll fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVQ4
AlphaFold — — full sequence — Viewing
ColabFold VK055_5066
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.513
3 0.004
5 0.004
2 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 13.03 0.589
2 1.28 0.011