Protein profile

VK055_5076

prokaryotic E2 E family protein

Genome: KpATCC43816

Gene: AIK83602.1 Structure source: AlphaFold + ColabFold UniProt A4GZH7
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Amino acids 362
Annotations 0
Features 6
PDB binders 0
Druggability 0.745

Overview

Basic information about this protein and its source genome.

Accession
VK055_5076
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83602.1
Status
annotated
Amino acids
362
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
89.76

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.745
Structure A4GZH7
Pocket Pocket 4
P2Rank 0.009
Structure A4GZH7
Pocket Pocket 1
ColabFold model
FPocket 0.664 · Pocket 2
P2Rank 0.008 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
241 358 Pfam PF14462 Prokaryotic E2 family E
241 358 InterPro IPR025701 Ubiquitin-conjugating enzyme, E2, family E
24 81 Pfam PF14452 Multiubiquitin
24 81 InterPro IPR027802 Multi-ubiquitin domain
89 153 Pfam PF14452 Multiubiquitin
89 153 InterPro IPR027802 Multi-ubiquitin domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A4GZH7
AlphaFold — — full sequence — Viewing
ColabFold VK055_5076
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.745