Protein profile

VK055_5089

type IV secretion system family protein

Genome: KpATCC43816

Gene: AIK83615.1 Structure source: AlphaFold + ColabFold UniProt A0A377Y288
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Amino acids 203
Annotations 0
Features 6
PDB binders 0
Druggability 0.038

Overview

Basic information about this protein and its source genome.

Accession
VK055_5089
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83615.1
Status
annotated
Amino acids
203
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
83.35

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.038
Structure A0A377Y288
Pocket Pocket 16
P2Rank 0.015
Structure A0A377Y288
Pocket Pocket 1
ColabFold model
FPocket 0.32 · Pocket 6
P2Rank 0.042 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 4 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
10 30 Coils Coil Coil
3 187 Gene3D G3DSA:1.20.58.430 -
3 187 InterPro IPR023220 Type IV secretion system, VirB5-domain
9 186 SUPERFAMILY SSF101082 Typo IV secretion system protein TraC
5 184 Pfam PF07996 Type IV secretion system proteins
5 184 InterPro IPR014158 Type IV secretion system, VirB5

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A377Y288
AlphaFold — — full sequence — Viewing
ColabFold VK055_5089
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 0.79 0.002
2 0.76 0.002