Protein profile

VK055_5099

bacterial regulatory, luxR family protein

Genome: KpATCC43816

Gene: AIK83625.1 Structure source: ColabFold
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Amino acids 133
Annotations 2
Features 12
PDB binders 0
Druggability 0.127

Overview

Basic information about this protein and its source genome.

Accession
VK055_5099
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83625.1
Status
annotated
Amino acids
133
Structure source
ColabFold
GO
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
63.52

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.127
Structure CB_VK055_5099
Pocket Pocket 13
P2Rank 0.007
Structure CB_VK055_5099
Pocket Pocket 1
ColabFold model
FPocket 0.127 · Pocket 13
P2Rank 0.007 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
69 120 Pfam PF00196 Bacterial regulatory proteins, luxR family
69 120 InterPro IPR000792 Transcription regulator LuxR, C-terminal
54 123 SUPERFAMILY SSF46894 C-terminal effector domain of the bipartite response regulators
54 123 InterPro IPR016032 Signal transduction response regulator, C-terminal effector
70 84 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature
70 84 InterPro IPR000792 Transcription regulator LuxR, C-terminal
100 112 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature
100 112 InterPro IPR000792 Transcription regulator LuxR, C-terminal
84 100 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature
84 100 InterPro IPR000792 Transcription regulator LuxR, C-terminal
42 127 Gene3D G3DSA:1.10.10.10 -
42 127 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed ColabFold model VK055_5099 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_5099
ColabFold — — full sequence — Viewing