Protein profile

VK055_5153

hypothetical protein

Genome: KpATCC43816

Gene: AIK83674.1 Structure source: AlphaFold + ColabFold UniProt A0A486V5D6
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Amino acids 261
Annotations 2
Features 5
PDB binders 0
Druggability 0.165

Overview

Basic information about this protein and its source genome.

Accession
VK055_5153
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83674.1
Status
annotated
Amino acids
261
Structure source
AlphaFold + ColabFold
GO
GO:0005694 A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0007059 The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
86.64

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.165
Structure A0A486V5D6
Pocket Pocket 10
P2Rank 0.126
Structure A0A486V5D6
Pocket Pocket 1
ColabFold model
FPocket 0.191 · Pocket 4
P2Rank 0.15 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 8 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005694 A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
  • GO:0007059 The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
46 124 SUPERFAMILY SSF110849 ParB/Sulfiredoxin
46 124 InterPro IPR036086 ParB/Sulfiredoxin superfamily
48 245 PANTHER PTHR33375 CHROMOSOME-PARTITIONING PROTEIN PARB-RELATED
111 219 Gene3D G3DSA:1.10.10.2830 -
117 221 SUPERFAMILY SSF109709 KorB DNA-binding domain-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A486V5D6
AlphaFold — — full sequence — Viewing
ColabFold VK055_5153
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.06 0.046