Protein profile

VK055_5162

phage antitermination Q family protein

Genome: KpATCC43816

Gene: AIK83683.1 Structure source: AlphaFold + ColabFold UniProt A0A486V764
Export view
Amino acids 192
Annotations 0
Features 2
PDB binders 0
Druggability 0.43

Overview

Basic information about this protein and its source genome.

Accession
VK055_5162
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83683.1
Status
annotated
Amino acids
192
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
58.989
DEG E-value
3.3e-71
Localization
Cytoplasmic
ColabFold pLDDT
73.93

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.43
Structure A0A486V764
Pocket Pocket 2
P2Rank 0.148
Structure A0A486V764
Pocket Pocket 1
ColabFold model
FPocket 0.733 · Pocket 9
P2Rank 0.312 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 9 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

2 records
Show feature table
Start End DB Term Name
1 177 Pfam PF06576 Protein of unknown function (DUF1133)
1 177 InterPro IPR010557 Protein of unknown function DUF1133

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A486V764
AlphaFold — — full sequence — Viewing
ColabFold VK055_5162
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.43
1 0.153
6 0.06
16 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.33 0.148
2 3.71 0.114
3 3.18 0.087
4 2.29 0.047
5 1.68 0.024