Protein profile

KP13_00061

hypothetical protein

Genome: KpKP13

Gene: AHE41985.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H4U5
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Amino acids 408
Annotations 0
Features 7
PDB binders 0
Druggability 0.634

Overview

Basic information about this protein and its source genome.

Accession
KP13_00061
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE41985.1
Status
annotated
Amino acids
408
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
97.44

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.634
Structure A0A0H3H4U5
Pocket Pocket 9
P2Rank 0.621
Structure A0A0H3H4U5
Pocket Pocket 1
ColabFold model
FPocket 0.491 · Pocket 2
P2Rank 0.561 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 111 / 4744 genomes with a hit
Normalized 0.023

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
219 407 Gene3D G3DSA:2.120.10.30 -
219 407 InterPro IPR011042 Six-bladed beta-propeller, TolB-like
63 179 Pfam PF12566 Protein of unknown function (DUF3748)
63 179 InterPro IPR022223 Protein of unknown function DUF3748
18 403 SUPERFAMILY SSF82171 DPP6 N-terminal domain-like
378 391 Pfam PF07676 WD40-like Beta Propeller Repeat
378 391 InterPro IPR011659 WD40-like beta propeller

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H4U5
AlphaFold — — full sequence — Viewing
ColabFold KP13_00061
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
9 0.634

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.49 0.453
2 4.32 0.179
3 3.47 0.126
4 1.06 0.007
5 0.79 0.002