Protein profile

KP13_00128

FMN-binding domain-containing protein

Genome: KpKP13

Gene: AHE42047.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GXI5
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Amino acids 208
Annotations 0
Features 7
PDB binders 0
Druggability 0.56

Overview

Basic information about this protein and its source genome.

Accession
KP13_00128
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42047.1
Status
annotated
Amino acids
208
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
91.58

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.56
Structure A0A0H3GXI5
Pocket Pocket 4
P2Rank 0.09
Structure A0A0H3GXI5
Pocket Pocket 1
ColabFold model
FPocket 0.633 · Pocket 4
P2Rank 0.138 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 10 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
32 154 Gene3D G3DSA:2.30.110.10 -
32 154 InterPro IPR012349 FMN-binding split barrel
33 191 PANTHER PTHR42815 FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED
46 132 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase
46 132 InterPro IPR011576 Pyridoxamine 5'-phosphate oxidase, putative
175 208 Coils Coil Coil
43 167 SUPERFAMILY SSF50475 FMN-binding split barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GXI5
AlphaFold — — full sequence — Viewing
ColabFold KP13_00128
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.56
16 0.001
1 0.0
15 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.25 0.09
2 2.38 0.051
3 1.87 0.031
4 1.49 0.017
5 1.34 0.013