Protein profile

KP13_00279

putative cellulose synthase operon protein D

Genome: KpKP13

Gene: AHE42190.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GUI8
Export view
Amino acids 158
Annotations 1
Features 4
PDB binders 0
Druggability 0.15

Overview

Basic information about this protein and its source genome.

Accession
KP13_00279
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42190.1
Status
annotated
Amino acids
158
Structure source
AlphaFold + ColabFold
GO
GO:0030244 The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
91.9

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.15
Structure A0A0H3GUI8
Pocket Pocket 7
P2Rank 0.343
Structure A0A0H3GUI8
Pocket Pocket 1
ColabFold model
FPocket 0.364 · Pocket 10
P2Rank 0.065 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 20 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0030244 The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
45 135 Pfam PF03500 Cellulose synthase subunit D
45 135 InterPro IPR022798 Cellulose synthase operon protein D, bacterial
59 157 Gene3D G3DSA:3.30.70.2590 -
59 157 InterPro IPR038470 Cellulose synthase subunit D superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GUI8
AlphaFold — — full sequence — Viewing
ColabFold KP13_00279
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.51 0.454
2 0.89 0.004