Protein profile

KP13_00282

Cellulose biosynthesis protein BcsF

Genome: KpKP13

Gene: bcsF AHE42193.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GYN1
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Amino acids 65
Annotations 0
Features 8
PDB binders 0
Druggability 0.349

Overview

Basic information about this protein and its source genome.

Accession
KP13_00282
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
bcsF AHE42193.1
Status
annotated
Amino acids
65
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
70.75

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.349
Structure A0A0H3GYN1
Pocket Pocket 4
P2Rank
Structure A0A0H3GYN1
Pocket No pockets
ColabFold model
FPocket 0.317 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 48 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
2 65 NCBIfam TIGR03493 cellulose biosynthesis protein BcsF
2 65 InterPro IPR019995 Cellulose biosynthesis, BcsF/YhjT
1 5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
5 24 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
6 24 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
25 65 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
2 59 Pfam PF11120 Cellulose biosynthesis protein BcsF
2 59 InterPro IPR019995 Cellulose biosynthesis, BcsF/YhjT

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GYN1
AlphaFold — — full sequence — Viewing
ColabFold KP13_00282
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.349
8 0.29
5 0.27
6 0.221