Protein profile

KP13_31569

Protein dcrB

Genome: KpKP13

Gene: dcrB AHE42241.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GUE1
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Amino acids 185
Annotations 1
Features 13
PDB binders 0
Druggability 0.172

Overview

Basic information about this protein and its source genome.

Accession
KP13_31569
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
dcrB AHE42241.1
Status
annotated
Amino acids
185
Structure source
AlphaFold + ColabFold
GO
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Periplasmic
ColabFold pLDDT
82.21

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.172
Structure A0A0H3GUE1
Pocket Pocket 11
P2Rank
Structure A0A0H3GUE1
Pocket No pockets
ColabFold model
FPocket 0.382 · Pocket 14
P2Rank 0.02 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 92 / 4744 genomes with a hit
Normalized 0.019

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
16 20 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 185 Hamap MF_02248 Inner membrane lipoprotein DcrB [dcrB].
1 185 InterPro IPR046406 Inner membrane lipoprotein DcrB
1 20 Phobius SIGNAL_PEPTIDE Signal peptide region
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 27 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
48 185 Gene3D G3DSA:3.40.1000.10 Mog1/PsbP, alpha/beta/alpha sandwich
51 181 Pfam PF08786 DcrB
51 181 InterPro IPR014894 Inner membrane lipoprotein DcrB/EagT6
1 19 SignalP_EUK SignalP-noTM SignalP-noTM
21 185 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
8 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 20 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GUE1
AlphaFold — — full sequence — Viewing
ColabFold KP13_31569
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer