Protein profile

KP13_00683

Ferrous iron transport protein C

Genome: KpKP13

Gene: AHE42303.1 feoC Structure source: Experimental + AlphaFold + ColabFold UniProt A6TF33|W9BMW4

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Amino acids 75

Annotations 0

Features 8

PDB binders 0

Druggability 0.659

Overview

Basic information about this protein and its source genome.

Accession: KP13_00683
Assembly: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene: AHE42303.1 feoC
Status: annotated
Amino acids: 75
Structure source: Experimental + AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Human identity (%): 0.0
Gut microbiome off-target: hit
Essential (DEG): N
DEG identity (%): 0.0
Localization: Unknown
ColabFold pLDDT: 80.08

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.659

Structure W9BMW4

Pocket Pocket 1

P2Rank

Structure A6TF33

Pocket No pockets

ColabFold model

FPocket 0.584 · Pocket 5

Core conservation Accessory gene

Roary core

CoreCruncher accessory

Gut microbiome 79 / 4744 genomes with a hit

Normalized 0.017

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
1	73	SUPERFAMILY	SSF46785	Winged helix DNA-binding domain
1	73	InterPro	IPR036390	Winged helix DNA-binding domain superfamily
1	75	Gene3D	G3DSA:1.10.10.10	-
1	75	InterPro	IPR036388	Winged helix-like DNA-binding domain superfamily
1	75	Hamap	MF_01586	Probable [Fe-S]-dependent transcriptional repressor [feoC].
1	75	InterPro	IPR023732	Probable [Fe-S]-dependent transcriptional repressor
2	64	Pfam	PF09012	FeoC like transcriptional regulator
2	64	InterPro	IPR015102	Transcriptional regulator HTH-type, FeoC

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

2 + 3

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
PDB 2K02	X-ray	20.00 Å	-	—	PDBe RCSB PDBj File	Viewing
PDB 7WQU	X-ray	20.00 Å	-	—	PDBe RCSB PDBj File	Loaded
AlphaFold AF_A6TF33	AlphaFold	—	—	full sequence	—	Loaded
AlphaFold AF_W9BMW4	AlphaFold	—	—	full sequence	—	Loaded
ColabFold KP13_00683	ColabFold	—	—	full sequence	—	Loaded

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK	Sticks	Spheres	Surfaces	Score	Probability	Labels	Zoom	Positions
1				3.0	0.098
2				2.07	0.046