Protein profile

KP13_02977

hypothetical protein

Genome: KpKP13

Gene: AHE42434.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GY68
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Amino acids 91
Annotations 0
Features 6
PDB binders 0
Druggability 0.204

Overview

Basic information about this protein and its source genome.

Accession
KP13_02977
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42434.1
Status
annotated
Amino acids
91
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
72.222
DEG E-value
5.85e-44
Localization
Unknown
ColabFold pLDDT
96.57

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.204
Structure A0A0H3GY68
Pocket Pocket 3
P2Rank
Structure A0A0H3GY68
Pocket No pockets
ColabFold model
FPocket 0.584 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 95 / 4744 genomes with a hit
Normalized 0.02

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
1 90 Gene3D G3DSA:3.30.370.10 -
1 90 InterPro IPR035905 Barstar-like superfamily
1 88 SUPERFAMILY SSF52038 Barstar-related
1 88 InterPro IPR035905 Barstar-like superfamily
5 79 Pfam PF01337 Barstar (barnase inhibitor)
5 79 InterPro IPR000468 Barstar (barnase inhibitor)

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GY68
AlphaFold — — full sequence — Viewing
ColabFold KP13_02977
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.204