Protein profile

KP13_01122

BolA domain-containing protein

Genome: KpKP13

Gene: AHE42484.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GY24
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Amino acids 84
Annotations 0
Features 10
PDB binders 0
Druggability 0.261

Overview

Basic information about this protein and its source genome.

Accession
KP13_01122
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42484.1
Status
annotated
Amino acids
84
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
35.0
Human E-value
2.86e-07
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
40.26
DEG E-value
1.09e-16
Localization
Unknown
ColabFold pLDDT
91.47

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.261
Structure A0A0H3GY24
Pocket Pocket 10
P2Rank
Structure A0A0H3GY24
Pocket No pockets
ColabFold model
FPocket 0.174 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 127 / 4744 genomes with a hit
Normalized 0.027

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
2 81 PANTHER PTHR46229 BOLA TRANSCRIPTION REGULATOR
1 84 FunFam G3DSA:3.30.300.90:FF:000002 Acid stress protein IbaG
1 84 Gene3D G3DSA:3.30.300.90 -
1 84 InterPro IPR036065 BolA-like superfamily
2 82 SUPERFAMILY SSF82657 BolA-like
2 82 InterPro IPR036065 BolA-like superfamily
1 83 PIRSF PIRSF003113 BolA
1 83 InterPro IPR002634 BolA protein
19 74 Pfam PF01722 BolA-like protein
19 74 InterPro IPR002634 BolA protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GY24
AlphaFold — — full sequence — Viewing
ColabFold KP13_01122
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
10 0.261
2 0.223