Protein profile

KP13_01120

Sugar fermentation stimulation protein B

Genome: KpKP13

Gene: sfsB AHE42486.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GTR9
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Amino acids 90
Annotations 1
Features 7
PDB binders 0
Druggability 0.216

Overview

Basic information about this protein and its source genome.

Accession
KP13_01120
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
sfsB AHE42486.1
Status
annotated
Amino acids
90
Structure source
AlphaFold + ColabFold
GO
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
89.72

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.216
Structure A0A0H3GTR9
Pocket Pocket 1
P2Rank
Structure A0A0H3GTR9
Pocket No pockets
ColabFold model
FPocket 0.598 · Pocket 3
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 111 / 4744 genomes with a hit
Normalized 0.023

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
2 70 Gene3D G3DSA:1.10.260.40 -
2 70 InterPro IPR010982 Lambda repressor-like, DNA-binding domain superfamily
1 70 FunFam G3DSA:1.10.260.40:FF:000017 DNA-binding transcriptional regulator SfsB
6 80 Pfam PF13693 Winged helix-turn-helix DNA-binding
6 80 InterPro IPR038722 Ner, winged helix-turn-helix DNA-binding domain
4 70 SUPERFAMILY SSF47413 lambda repressor-like DNA-binding domains
4 70 InterPro IPR010982 Lambda repressor-like, DNA-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GTR9
AlphaFold — — full sequence — Viewing
ColabFold KP13_01120
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.216