Protein profile

KP13_01104

hypothetical protein

Genome: KpKP13

Gene: AHE42503.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GW55
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Amino acids 219
Annotations 0
Features 6
PDB binders 0
Druggability 0.846

Overview

Basic information about this protein and its source genome.

Accession
KP13_01104
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42503.1
Status
annotated
Amino acids
219
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
94.18

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.846
Structure A0A0H3GW55
Pocket Pocket 1
P2Rank 0.955
Structure A0A0H3GW55
Pocket Pocket 1
ColabFold model
FPocket 0.939 · Pocket 1
P2Rank 0.968 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 18 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
30 213 Gene3D G3DSA:2.60.120.10 Jelly Rolls
30 213 InterPro IPR014710 RmlC-like jelly roll fold
149 217 Pfam PF15977 Winged helix-turn-helix DNA binding
149 217 InterPro IPR041687 IprA, winged helix-turn-helix domain
27 124 SUPERFAMILY SSF51206 cAMP-binding domain-like
27 124 InterPro IPR018490 Cyclic nucleotide-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GW55
AlphaFold — — full sequence — Viewing
ColabFold KP13_01104
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.846

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 28.91 0.928
2 2.86 0.09
3 1.9 0.038