Protein profile

KP13_01102

Ribosome maturation factor rimP

Genome: KpKP13

Gene: rimP AHE42506.1 Structure source: AlphaFold + ColabFold UniProt A6TEI9
Export view
Amino acids 140
Annotations 1
Features 19
PDB binders 0
Druggability 0.317

Overview

Basic information about this protein and its source genome.

Accession
KP13_01102
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
rimP AHE42506.1
Status
annotated
Amino acids
140
Structure source
AlphaFold + ColabFold
GO
GO:0042274 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
95.0
DEG E-value
4.4200000000000005e-99
Localization
Cytoplasmic
ColabFold pLDDT
94.88

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.317
Structure A6TEI9
Pocket Pocket 5
P2Rank 0.032
Structure A6TEI9
Pocket Pocket 1
ColabFold model
FPocket 0.484 · Pocket 6
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 138 / 4744 genomes with a hit
Normalized 0.029

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0042274 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.

Sequence Features

Domain/signature hits from InterPro and related databases.

19 records
Show feature table
Start End DB Term Name
4 140 Hamap MF_01077 Ribosome maturation factor RimP [rimP].
4 140 InterPro IPR003728 Ribosome maturation factor RimP
4 72 SUPERFAMILY SSF75420 YhbC-like, N-terminal domain
4 72 InterPro IPR035956 RimP, N-terminal domain superfamily
75 140 Pfam PF17384 RimP C-terminal SH3 domain
75 140 InterPro IPR028998 Ribosome maturation factor RimP, C-terminal
70 140 CDD cd01734 YlxS_C
70 140 InterPro IPR028998 Ribosome maturation factor RimP, C-terminal
2 140 PANTHER PTHR33867 RIBOSOME MATURATION FACTOR RIMP
2 140 InterPro IPR003728 Ribosome maturation factor RimP
77 137 Gene3D G3DSA:2.30.30.180 -
1 69 Gene3D G3DSA:3.30.300.70 -
1 69 InterPro IPR035956 RimP, N-terminal domain superfamily
73 140 SUPERFAMILY SSF74942 YhbC-like, C-terminal domain
73 140 InterPro IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily
1 69 FunFam G3DSA:3.30.300.70:FF:000001 Ribosome maturation factor RimP
3 72 Pfam PF02576 RimP N-terminal domain
3 72 InterPro IPR028989 Ribosome maturation factor RimP, N-terminal
77 137 FunFam G3DSA:2.30.30.180:FF:000001 Ribosome maturation factor RimP

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A6TEI9
AlphaFold — — full sequence — Viewing
ColabFold KP13_01102
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.317

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.76 0.032