Protein profile

KP13_02886

Pirin-like protein

Genome: KpKP13

Gene: AHE42544.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H3D3
Export view
Amino acids 235
Annotations 0
Features 15
PDB binders 0
Druggability 0.235

Overview

Basic information about this protein and its source genome.

Accession
KP13_02886
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42544.1
Status
annotated
Amino acids
235
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
83.02

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.235
Structure A0A0H3H3D3
Pocket Pocket 5
P2Rank 0.245
Structure A0A0H3H3D3
Pocket Pocket 1
ColabFold model
FPocket 0.421 · Pocket 13
P2Rank 0.497 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 103 / 4744 genomes with a hit
Normalized 0.022

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 232 PIRSF PIRSF006232 Pirin
1 232 InterPro IPR012093 Pirin
137 235 Gene3D G3DSA:2.60.120.10 Jelly Rolls
137 235 InterPro IPR014710 RmlC-like jelly roll fold
144 233 Pfam PF17954 Quercetinase C-terminal cupin domain
144 233 InterPro IPR041602 Quercetin 2,3-dioxygenase, C-terminal cupin domain
14 136 Gene3D G3DSA:2.60.120.10 Jelly Rolls
14 136 InterPro IPR014710 RmlC-like jelly roll fold
161 234 CDD cd20311 cupin_Yhhw_C
3 233 SUPERFAMILY SSF51182 RmlC-like cupins
3 233 InterPro IPR011051 RmlC-like cupin domain superfamily
7 121 Pfam PF02678 Pirin
7 121 InterPro IPR003829 Pirin, N-terminal domain
3 234 PANTHER PTHR43212 QUERCETIN 2,3-DIOXYGENASE
3 234 InterPro IPR012093 Pirin

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H3D3
AlphaFold — — full sequence — Viewing
ColabFold KP13_02886
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.235
4 0.221

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.64 0.202