Protein profile

KP13_02842

Diol/glycerol dehydratase reactivating factor, small subunit

Genome: KpKP13

Gene: AHE42589.1 Structure source: Experimental + ColabFold UniProt Q48423
Export view
Amino acids 117
Annotations 1
Features 8
PDB binders 0
Druggability 0.283

Overview

Basic information about this protein and its source genome.

Accession
KP13_02842
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42589.1
Status
annotated
Amino acids
117
Structure source
Experimental + ColabFold
GO
GO:0046872 Binding to a metal ion.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
94.73

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.283
Structure 1NBW
Pocket Pocket 1
P2Rank
Structure 1NBW
Pocket No pockets
ColabFold model
FPocket 0.165 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 15 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 117 Gene3D G3DSA:3.40.50.10150 -
1 117 InterPro IPR010254 B12-dependent dehydratases, beta subunit
2 116 SUPERFAMILY SSF52968 B12-dependent dehydatase associated subunit
2 116 InterPro IPR010254 B12-dependent dehydratases, beta subunit
1 116 PIRSF PIRSF011503 DdrB_PduH
1 116 InterPro IPR009192 Diol/glycerol dehydratase reactivating factor, small subunit
7 113 Pfam PF02288 Dehydratase medium subunit
7 113 InterPro IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 1NBW
X-ray 2.40 Å B,D
100.0% 1-117
PDBe RCSB PDBj File
Viewing
ColabFold KP13_02842
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
80 0.853
73 0.411
59 0.281

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 41.76 0.967
2 34.33 0.95
3 14.0 0.707
4 6.31 0.317
5 5.08 0.232