Protein profile

KP13_02794

hypothetical protein

Genome: KpKP13

Gene: AHE42637.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GXR7
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Amino acids 140
Annotations 0
Features 4
PDB binders 0
Druggability 0.15

Overview

Basic information about this protein and its source genome.

Accession
KP13_02794
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42637.1
Status
annotated
Amino acids
140
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
92.806
DEG E-value
1.4e-97
Localization
Unknown
ColabFold pLDDT
82.21

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.15
Structure A0A0H3GXR7
Pocket Pocket 1
P2Rank 0.044
Structure A0A0H3GXR7
Pocket Pocket 1
ColabFold model
FPocket 0.678 · Pocket 2
P2Rank 0.079 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 97 / 4744 genomes with a hit
Normalized 0.02

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
21 134 Pfam PF06853 Protein of unknown function (DUF1249)
21 134 InterPro IPR009659 Protein of unknown function DUF1249
2 140 PANTHER PTHR38774 CYTOPLASMIC PROTEIN-RELATED
2 140 InterPro IPR009659 Protein of unknown function DUF1249

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GXR7
AlphaFold — — full sequence — Viewing
ColabFold KP13_02794
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.91 0.039
2 1.6 0.025
3 1.1 0.008