Protein profile

KP13_02792

Esterase

Genome: KpKP13

Gene: AHE42639.1 Structure source: Experimental + ColabFold UniProt A0A0W8AWE3
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Amino acids 191
Annotations 0
Features 8
PDB binders 0
Druggability 0.251

Overview

Basic information about this protein and its source genome.

Accession
KP13_02792
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42639.1
Status
annotated
Amino acids
191
Structure source
Experimental + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
97.71

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.251
Structure 9BI7
Pocket Pocket 7
P2Rank 0.613
Structure 9BI7
Pocket Pocket 1
ColabFold model
FPocket 0.361 · Pocket 7
P2Rank 0.595 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 120 / 4744 genomes with a hit
Normalized 0.025

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 190 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
1 190 InterPro IPR029058 Alpha/Beta hydrolase fold
1 190 PANTHER PTHR35602 ESTERASE YQIA-RELATED
1 190 InterPro IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA
4 188 Pfam PF05728 Uncharacterised protein family (UPF0227)
4 188 InterPro IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA
3 188 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
3 188 InterPro IPR029058 Alpha/Beta hydrolase fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 9BI7
X-ray 1.50 Å A
100.0% 1-191
PDBe RCSB PDBj File
Viewing
ColabFold KP13_02792
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.251

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.49 0.613