Protein profile

KP13_02755

hypothetical protein

Genome: KpKP13

Gene: AHE42676.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVL4
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Amino acids 97
Annotations 2
Features 7
PDB binders 0
Druggability 0.131

Overview

Basic information about this protein and its source genome.

Accession
KP13_02755
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42676.1
Status
annotated
Amino acids
97
Structure source
AlphaFold + ColabFold
GO
GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
89.18

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.131
Structure A0A0H3GVL4
Pocket Pocket 5
P2Rank
Structure A0A0H3GVL4
Pocket No pockets
ColabFold model
FPocket 0.123 · Pocket 7
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 13 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
7 91 Gene3D G3DSA:1.20.5.780 Single helix bin
14 88 Pfam PF08681 Protein of unknown function (DUF1778)
14 88 InterPro IPR014795 Vibrio phage ICP1, Orf50
3 95 PANTHER PTHR35401 COPG FAMILY HELIX-TURN-HELIX PROTEIN-RELATED-RELATED
3 95 InterPro IPR014795 Vibrio phage ICP1, Orf50
10 87 SUPERFAMILY SSF47598 Ribbon-helix-helix
10 87 InterPro IPR010985 Ribbon-helix-helix

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GVL4 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVL4
AlphaFold — — full sequence — Viewing
ColabFold KP13_02755
ColabFold — — full sequence — Loaded