Protein profile

KP13_02738

hypothetical protein

Genome: KpKP13

Gene: AHE42694.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GT56
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Amino acids 100
Annotations 1
Features 14
PDB binders 0
Druggability 0.184

Overview

Basic information about this protein and its source genome.

Accession
KP13_02738
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42694.1
Status
annotated
Amino acids
100
Structure source
AlphaFold + ColabFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
34.211
Human E-value
7.22e-11
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
80.13

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.184
Structure A0A0H3GT56
Pocket Pocket 6
P2Rank 0.007
Structure A0A0H3GT56
Pocket Pocket 1
ColabFold model
FPocket 0.242 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 126 / 4744 genomes with a hit
Normalized 0.027

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
12 91 PANTHER PTHR13420 UNCHARACTERIZED
12 91 InterPro IPR003746 Protein of unknown function DUF167
14 85 Pfam PF02594 Uncharacterised ACR, YggU family COG1872
14 85 InterPro IPR003746 Protein of unknown function DUF167
1 100 Gene3D G3DSA:3.30.1200.10 -
1 100 InterPro IPR036591 YggU-like superfamily
11 97 Hamap MF_00634 UPF0235 protein YggU [yggU].
11 97 InterPro IPR003746 Protein of unknown function DUF167
11 87 SMART SM01152 DUF167_2
11 87 InterPro IPR003746 Protein of unknown function DUF167
16 85 NCBIfam TIGR00251 DUF167 family protein
16 85 InterPro IPR003746 Protein of unknown function DUF167
4 96 SUPERFAMILY SSF69786 YggU-like
4 96 InterPro IPR036591 YggU-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GT56
AlphaFold — — full sequence — Viewing
ColabFold KP13_02738
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.19 0.01