Protein profile

KP13_02710

putative deoxythimodone diphosphates-4-dehydrorhamnose 3,5-epimerase

Genome: KpKP13

Gene: AHE42722.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H2R0
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Amino acids 176
Annotations 0
Features 8
PDB binders 0
Druggability 0.777

Overview

Basic information about this protein and its source genome.

Accession
KP13_02710
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42722.1
Status
annotated
Amino acids
176
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.61

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.777
Structure A0A0H3H2R0
Pocket Pocket 1
P2Rank 0.777
Structure A0A0H3H2R0
Pocket Pocket 1
ColabFold model
FPocket 0.923 · Pocket 1
P2Rank 0.827 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 37 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
83 150 Pfam PF07883 Cupin domain
83 150 InterPro IPR013096 Cupin 2, conserved barrel
25 155 PANTHER PTHR43346 LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED
24 175 CDD cd02225 cupin_PA3510-like
42 176 Gene3D G3DSA:2.60.120.10 Jelly Rolls
42 176 InterPro IPR014710 RmlC-like jelly roll fold
46 170 SUPERFAMILY SSF51182 RmlC-like cupins
46 170 InterPro IPR011051 RmlC-like cupin domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H2R0
AlphaFold — — full sequence — Viewing
ColabFold KP13_02710
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.777

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.18 0.6
2 1.56 0.024