Protein profile

KP13_31801

putative oxidative stress defense protein

Genome: KpKP13

Gene: AHE42735.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H2P7
Export view
Amino acids 255
Annotations 0
Features 13
PDB binders 0
Druggability 0.494

Overview

Basic information about this protein and its source genome.

Accession
KP13_31801
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42735.1
Status
annotated
Amino acids
255
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Periplasmic
ColabFold pLDDT
83.45

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.494
Structure A0A0H3H2P7
Pocket Pocket 12
P2Rank 0.008
Structure A0A0H3H2P7
Pocket Pocket 1
ColabFold model
FPocket 0.685 · Pocket 11
P2Rank 0.025 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 114 / 4744 genomes with a hit
Normalized 0.024

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
33 232 Gene3D G3DSA:3.30.110.170 Protein of unknown function (DUF541), domain 1
30 231 Pfam PF04402 Protein of unknown function (DUF541)
30 231 InterPro IPR007497 Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541
5 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
17 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
234 255 MobiDBLite mobidb-lite consensus disorder prediction
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
22 255 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 21 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
42 148 Gene3D G3DSA:3.30.70.2970 Protein of unknown function (DUF541), domain 2
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 234 PANTHER PTHR34387 SLR1258 PROTEIN
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H2P7
AlphaFold — — full sequence — Viewing
ColabFold KP13_31801
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
12 0.494
1 0.003
13 0.003
3 0.001

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.14 0.008
2 0.84 0.003