Protein profile

KP13_02184

hypothetical protein

Genome: KpKP13

Gene: AHE42753.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H2M9
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Amino acids 203
Annotations 0
Features 18
PDB binders 0
Druggability 0.503

Overview

Basic information about this protein and its source genome.

Accession
KP13_02184
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42753.1
Status
annotated
Amino acids
203
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
91.4

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.503
Structure A0A0H3H2M9
Pocket Pocket 5
P2Rank
Structure A0A0H3H2M9
Pocket No pockets
ColabFold model
FPocket 0.43 · Pocket 7
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 59 / 4744 genomes with a hit
Normalized 0.012

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
46 194 CDD cd03023 DsbA_Com1_like
19 203 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
32 194 SUPERFAMILY SSF52833 Thioredoxin-like
32 194 InterPro IPR036249 Thioredoxin-like superfamily
1 18 SignalP_EUK SignalP-noTM SignalP-noTM
8 198 ProSiteProfiles PS51352 Thioredoxin domain profile.
8 198 InterPro IPR013766 Thioredoxin domain
40 194 Pfam PF13462 Thioredoxin
40 194 InterPro IPR012336 Thioredoxin-like fold
1 18 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
54 72 ProSitePatterns PS00194 Thioredoxin family active site.
54 72 InterPro IPR017937 Thioredoxin, conserved site
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
46 195 PANTHER PTHR35272 THIOL:DISULFIDE INTERCHANGE PROTEIN DSBC-RELATED
3 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
16 201 Gene3D G3DSA:3.40.30.10 Glutaredoxin

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H2M9
AlphaFold — — full sequence — Viewing
ColabFold KP13_02184
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
8 0.016
9 0.009
1 0.001
6 0.001