Protein profile

KP13_31804

ASCH family protein

Genome: KpKP13

Gene: AHE42758.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H2M4
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Amino acids 103
Annotations 0
Features 15
PDB binders 0
Druggability 0.655

Overview

Basic information about this protein and its source genome.

Accession
KP13_31804
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42758.1
Status
annotated
Amino acids
103
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
84.466
DEG E-value
5.16e-63
Localization
Unknown
ColabFold pLDDT
82.07

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.655
Structure A0A0H3H2M4
Pocket Pocket 1
P2Rank 0.389
Structure A0A0H3H2M4
Pocket Pocket 1
ColabFold model
FPocket 0.444 · Pocket 1
P2Rank 0.393 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 87 / 4744 genomes with a hit
Normalized 0.018

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 103 FunFam G3DSA:2.30.130.30:FF:000001 UPF0267 protein YqfB
5 101 CDD cd06552 ASCH_yqfb_like
1 103 PIRSF PIRSF029143 UCP029143
1 103 InterPro IPR008314 N(4)-acetylcytidine amidohydrolase
1 102 PANTHER PTHR38088 UCP029143 FAMILY PROTEIN
1 102 InterPro IPR008314 N(4)-acetylcytidine amidohydrolase
6 103 SMART SM01022 ASCH_2
6 103 InterPro IPR007374 ASCH domain
3 103 Hamap MF_00684 N(4)-acetylcytidine amidohydrolase.
3 103 InterPro IPR008314 N(4)-acetylcytidine amidohydrolase
1 103 Gene3D G3DSA:2.30.130.30 Hypothetical protein.
2 102 SUPERFAMILY SSF88697 PUA domain-like
2 102 InterPro IPR015947 PUA-like superfamily
6 100 Pfam PF04266 ASCH domain
6 100 InterPro IPR007374 ASCH domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H2M4
AlphaFold — — full sequence — Viewing
ColabFold KP13_31804
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.655

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.25 0.313