Protein profile

KP13_02308

putative propanediol utilization protein

Genome: KpKP13

Gene: AHE42879.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GSK3
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Amino acids 91
Annotations 1
Features 10
PDB binders 0
Druggability 0.005

Overview

Basic information about this protein and its source genome.

Accession
KP13_02308
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42879.1
Status
annotated
Amino acids
91
Structure source
AlphaFold + ColabFold
GO
GO:0031469 An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
44.444
DEG E-value
6.01e-17
Localization
Unknown
ColabFold pLDDT
94.74

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.005
Structure A0A0H3GSK3
Pocket Pocket 2
P2Rank
Structure A0A0H3GSK3
Pocket No pockets
ColabFold model
FPocket 0.045 · Pocket 2
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 56 / 4744 genomes with a hit
Normalized 0.012

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0031469 An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 87 CDD cd01614 EutN_CcmL
1 87 InterPro IPR004992 Ethanolamine utilization protein EutN/carboxysome shell vertex protein CcmL
1 87 ProSiteProfiles PS51932 Bacterial microcompartment vertex (BMV) domain profile.
1 91 Gene3D G3DSA:2.40.50.220 EutN/Ccml
1 91 InterPro IPR036677 EutN/Ccml superfamily
1 89 SUPERFAMILY SSF159133 EutN/CcmL-like
1 89 InterPro IPR036677 EutN/Ccml superfamily
1 90 PANTHER PTHR36539 ETHANOLAMINE UTILIZATION PROTEIN EUTN
1 90 InterPro IPR004992 Ethanolamine utilization protein EutN/carboxysome shell vertex protein CcmL
1 87 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GSK3 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GSK3
AlphaFold — — full sequence — Viewing
ColabFold KP13_02308
ColabFold — — full sequence — Loaded