Protein profile

KP13_02313

Propanediol utilization protein PduH

Genome: KpKP13

Gene: AHE42884.1 pduH Structure source: AlphaFold + ColabFold UniProt A0A0H3GSJ7
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Amino acids 116
Annotations 0
Features 8
PDB binders 0
Druggability 0.136

Overview

Basic information about this protein and its source genome.

Accession
KP13_02313
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42884.1 pduH
Status
annotated
Amino acids
116
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
93.57

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.136
Structure A0A0H3GSJ7
Pocket Pocket 1
P2Rank
Structure A0A0H3GSJ7
Pocket No pockets
ColabFold model
FPocket 0.236 · Pocket 1
P2Rank 0.002 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 42 / 4744 genomes with a hit
Normalized 0.009

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 114 PIRSF PIRSF011503 DdrB_PduH
1 114 InterPro IPR009192 Diol/glycerol dehydratase reactivating factor, small subunit
7 111 Pfam PF02288 Dehydratase medium subunit
7 111 InterPro IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor
2 115 SUPERFAMILY SSF52968 B12-dependent dehydatase associated subunit
2 115 InterPro IPR010254 B12-dependent dehydratases, beta subunit
1 116 Gene3D G3DSA:3.40.50.10150 -
1 116 InterPro IPR010254 B12-dependent dehydratases, beta subunit

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GSJ7
AlphaFold — — full sequence — Viewing
ColabFold KP13_02313
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer