Protein profile

KP13_02316

Propanediol dehydratase medium subunit

Genome: KpKP13

Gene: AHE42887.1 pduD Structure source: AlphaFold + ColabFold UniProt A0A0H3GX01
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Amino acids 229
Annotations 0
Features 8
PDB binders 0
Druggability 0.754

Overview

Basic information about this protein and its source genome.

Accession
KP13_02316
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42887.1 pduD
Status
annotated
Amino acids
229
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.77

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.754
Structure A0A0H3GX01
Pocket Pocket 14
P2Rank 0.065
Structure A0A0H3GX01
Pocket Pocket 1
ColabFold model
FPocket 0.559 · Pocket 1
P2Rank 0.062 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 165 / 4744 genomes with a hit
Normalized 0.035

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
52 228 SUPERFAMILY SSF52968 B12-dependent dehydatase associated subunit
52 228 InterPro IPR010254 B12-dependent dehydratases, beta subunit
1 229 PIRSF PIRSF018506 Prpndl_dhdrts_md
1 229 InterPro IPR025541 Propanediol/glycerol dehydratase, medium subunit
74 186 Pfam PF02288 Dehydratase medium subunit
74 186 InterPro IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor
45 229 Gene3D G3DSA:3.40.50.10150 -
45 229 InterPro IPR010254 B12-dependent dehydratases, beta subunit

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GX01
AlphaFold — — full sequence — Viewing
ColabFold KP13_02316
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
14 0.754