Protein profile

KP13_02374

Protein syd

Genome: KpKP13

Gene: AHE42945.1 syd Structure source: AlphaFold + ColabFold UniProt A0A0H3GXI3
Export view
Amino acids 181
Annotations 1
Features 8
PDB binders 0
Druggability 0.432

Overview

Basic information about this protein and its source genome.

Accession
KP13_02374
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE42945.1 syd
Status
annotated
Amino acids
181
Structure source
AlphaFold + ColabFold
GO
GO:0009898 The leaflet of the plasma membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
97.66

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.432
Structure A0A0H3GXI3
Pocket Pocket 7
P2Rank 0.241
Structure A0A0H3GXI3
Pocket Pocket 1
ColabFold model
FPocket 0.333 · Pocket 9
P2Rank 0.232 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 104 / 4744 genomes with a hit
Normalized 0.022

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0009898 The leaflet of the plasma membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
3 181 Hamap MF_01104 Protein Syd [syd].
3 181 InterPro IPR009948 Syd
1 181 Gene3D G3DSA:3.40.1580.20 Syd protein
1 181 InterPro IPR038228 Syd superfamily
7 179 Pfam PF07348 Syd protein (SUKH-2)
7 179 InterPro IPR009948 Syd
7 177 CDD cd16323 Syd
7 177 InterPro IPR009948 Syd

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GXI3
AlphaFold — — full sequence — Viewing
ColabFold KP13_02374
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.432

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.41 0.065
2 2.13 0.049
3 1.25 0.012
4 1.08 0.007