Protein profile

KP13_16511

Regulatory protein recX

Genome: KpKP13

Gene: recX ANJ86585.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H1V2
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Amino acids 166
Annotations 2
Features 13
PDB binders 0
Druggability 0.194

Overview

Basic information about this protein and its source genome.

Accession
KP13_16511
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
recX ANJ86585.1
Status
annotated
Amino acids
166
Structure source
AlphaFold + ColabFold
GO
GO:0006282 Any process that modulates the frequency, rate or extent of DNA repair. GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.19

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.194
Structure A0A0H3H1V2
Pocket Pocket 3
P2Rank
Structure A0A0H3H1V2
Pocket No pockets
ColabFold model
FPocket 0.209 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 69 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0006282 Any process that modulates the frequency, rate or extent of DNA repair.
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
50 162 Pfam PF02631 RecX family
50 162 InterPro IPR003783 Regulatory protein RecX
10 166 Hamap MF_01114 Regulatory protein RecX [recX].
10 166 InterPro IPR003783 Regulatory protein RecX
8 69 Gene3D G3DSA:1.10.10.10 -
8 69 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
116 166 Gene3D G3DSA:1.10.10.10 -
116 166 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
70 115 FunFam G3DSA:1.10.10.10:FF:000134 Regulatory protein RecX
5 163 PANTHER PTHR33602 REGULATORY PROTEIN RECX FAMILY PROTEIN
5 163 InterPro IPR003783 Regulatory protein RecX
70 115 Gene3D G3DSA:1.10.10.10 -
70 115 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H1V2
AlphaFold — — full sequence — Viewing
ColabFold KP13_16511
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer