Protein profile

KP13_02459

putative fimbrial protein

Genome: KpKP13

Gene: AHE43105.1 Structure source: AlphaFold + ColabFold UniProt A0A1C1IAQ7
Export view
Amino acids 342
Annotations 2
Features 12
PDB binders 0
Druggability 0.021

Overview

Basic information about this protein and its source genome.

Accession
KP13_02459
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43105.1
Status
annotated
Amino acids
342
Structure source
AlphaFold + ColabFold
GO
GO:0007155 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289 A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
87.58

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.021
Structure A0A1C1IAQ7
Pocket Pocket 1
P2Rank 0.624
Structure A0A1C1IAQ7
Pocket Pocket 1
ColabFold model
FPocket 0.122 · Pocket 1
P2Rank 0.517 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 1 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0007155 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
  • GO:0009289 A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 26 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
27 342 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
1 26 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
20 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 28 SignalP_EUK SignalP-noTM SignalP-noTM
200 341 Pfam PF00419 Fimbrial protein
200 341 InterPro IPR000259 Fimbrial-type adhesion domain
210 341 SUPERFAMILY SSF49401 Bacterial adhesins
210 341 InterPro IPR008966 Adhesion domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A1C1IAQ7
AlphaFold — — full sequence — Viewing
ColabFold KP13_02459
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.41 0.609
2 2.48 0.068