Protein profile

KP13_02433

Protein rnfH

Genome: KpKP13

Gene: AHE43131.1 rnfH Structure source: AlphaFold + ColabFold UniProt A0A0H3GWG6
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Amino acids 96
Annotations 0
Features 10
PDB binders 0
Druggability 0.121

Overview

Basic information about this protein and its source genome.

Accession
KP13_02433
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43131.1 rnfH
Status
annotated
Amino acids
96
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
85.417
DEG E-value
4.1799999999999993e-54
Localization
Unknown
ColabFold pLDDT
79.53

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.121
Structure A0A0H3GWG6
Pocket Pocket 4
P2Rank
Structure A0A0H3GWG6
Pocket No pockets
ColabFold model
FPocket 0.159 · Pocket 4
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 147 / 4744 genomes with a hit
Normalized 0.031

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
3 95 PANTHER PTHR37483 UPF0125 PROTEIN RATB
3 95 InterPro IPR005346 RnfH protein
5 87 Pfam PF03658 RnfH family Ubiquitin
5 87 InterPro IPR005346 RnfH protein
5 79 SUPERFAMILY SSF54285 MoaD/ThiS
5 79 InterPro IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp
5 95 Hamap MF_00460 Protein RnfH [rnfH].
5 95 InterPro IPR005346 RnfH protein
1 89 Gene3D G3DSA:3.10.20.280 -
1 89 InterPro IPR037021 RnfH superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GWG6 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GWG6
AlphaFold — — full sequence — Viewing
ColabFold KP13_02433
ColabFold — — full sequence — Loaded