Protein profile

KP13_00873

phage modification methylase MunI

Genome: KpKP13

Gene: AHE43236.1 munIM Structure source: AlphaFold + ColabFold UniProt A0A2Z6EEF6
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Amino acids 197
Annotations 2
Features 7
PDB binders 0
Druggability 0.506

Overview

Basic information about this protein and its source genome.

Accession
KP13_00873
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43236.1 munIM
Status
annotated
Amino acids
197
Structure source
AlphaFold + ColabFold
GO
GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0032259 The process in which a methyl group is covalently attached to a molecule.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.79

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.506
Structure A0A2Z6EEF6
Pocket Pocket 7
P2Rank 0.549
Structure A0A2Z6EEF6
Pocket Pocket 1
ColabFold model
FPocket 0.242 · Pocket 10
P2Rank 0.642 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 11 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.
  • GO:0032259 The process in which a methyl group is covalently attached to a molecule.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
1 195 ProSiteProfiles PS51143 MT-A70-like family profile.
1 195 InterPro IPR007757 MT-A70-like
4 152 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases
4 152 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
5 174 Pfam PF05063 MT-A70
5 174 InterPro IPR007757 MT-A70-like
4 176 PANTHER PTHR12829 N6-ADENOSINE-METHYLTRANSFERASE

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A2Z6EEF6
AlphaFold — — full sequence — Viewing
ColabFold KP13_00873
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.506

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.82 0.35
2 4.85 0.216
3 1.95 0.041