Protein profile

KP13_00896

PBSX phage terminase small subunit

Genome: KpKP13

Gene: AHE43259.1 Structure source: AlphaFold + ColabFold UniProt A0A5D3JUW0
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Amino acids 199
Annotations 1
Features 5
PDB binders 0
Druggability 0.167

Overview

Basic information about this protein and its source genome.

Accession
KP13_00896
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43259.1
Status
annotated
Amino acids
199
Structure source
AlphaFold + ColabFold
GO
GO:0051276 A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
83.83

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.167
Structure A0A5D3JUW0
Pocket Pocket 10
P2Rank
Structure A0A5D3JUW0
Pocket No pockets
ColabFold model
FPocket 0.76 · Pocket 3
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 13 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0051276 A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
18 175 Pfam PF03592 Terminase small subunit
18 175 InterPro IPR005335 Terminase small subunit
14 78 Gene3D G3DSA:1.10.10.1400 -
14 78 InterPro IPR038713 Terminase small subunit, N-terminal DNA-binding domain, HTH motif superfamily
19 173 PANTHER PTHR41328 TERMINASE SMALL SUBUNIT-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A5D3JUW0
AlphaFold — — full sequence — Viewing
ColabFold KP13_00896
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer