Protein profile

KP13_00901

Bacteriophage head-to-tail connecting protein

Genome: KpKP13

Gene: AHE43264.1 Structure source: AlphaFold + ColabFold UniProt A0A844PS52
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Amino acids 559
Annotations 0
Features 4
PDB binders 0
Druggability 0.662

Overview

Basic information about this protein and its source genome.

Accession
KP13_00901
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43264.1
Status
annotated
Amino acids
559
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
83.98

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.662
Structure A0A844PS52
Pocket Pocket 2
P2Rank 0.246
Structure A0A844PS52
Pocket Pocket 1
ColabFold model
FPocket 0.727 · Pocket 2
P2Rank 0.314 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 11 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
497 517 Coils Coil Coil
514 559 MobiDBLite mobidb-lite consensus disorder prediction
16 501 Pfam PF12236 Bacteriophage head to tail connecting protein
16 501 InterPro IPR020991 Head-to-tail connector protein, podovirus-type

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A844PS52
AlphaFold — — full sequence — Viewing
ColabFold KP13_00901
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.662
26 0.616
8 0.32

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.94 0.156
2 1.89 0.038
3 1.61 0.026
4 1.32 0.015