Protein profile

KP13_00913

hypothetical protein

Genome: KpKP13

Gene: AHE43276.1 Structure source: AlphaFold + ColabFold UniProt A0A377Y9B2
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Amino acids 1129
Annotations 0
Features 6
PDB binders 0
Druggability 0.681

Overview

Basic information about this protein and its source genome.

Accession
KP13_00913
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43276.1
Status
annotated
Amino acids
1129
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
83.31

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.681
Structure A0A377Y9B2
Pocket Pocket 83
P2Rank 0.869
Structure A0A377Y9B2
Pocket Pocket 1
ColabFold model
FPocket 0.877 · Pocket 1
P2Rank 0.943 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 3 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
530 575 Pfam PF06034 Nucleopolyhedrovirus protein of unknown function (DUF919)
530 575 InterPro IPR009265 Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf29
1007 1129 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
442 462 Coils Coil Coil
987 1006 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 986 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A377Y9B2
AlphaFold — — full sequence — Viewing
ColabFold KP13_00913
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
83 0.681
77 0.567

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 19.2 0.836
2 18.0 0.813
3 11.15 0.598
4 9.09 0.487
5 5.8 0.283