Protein profile

KP13_03827

hypothetical protein

Genome: KpKP13

Gene: AHE43311.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H1C8
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Amino acids 291
Annotations 1
Features 10
PDB binders 0
Druggability 0.948

Overview

Basic information about this protein and its source genome.

Accession
KP13_03827
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43311.1
Status
annotated
Amino acids
291
Structure source
AlphaFold + ColabFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
86.46

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.948
Structure A0A0H3H1C8
Pocket Pocket 1
P2Rank 0.966
Structure A0A0H3H1C8
Pocket Pocket 1
ColabFold model
FPocket 0.79 · Pocket 19
P2Rank 0.838 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 169 / 4744 genomes with a hit
Normalized 0.036

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
61 291 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 30 MobiDBLite mobidb-lite consensus disorder prediction
39 61 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 39 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 15 MobiDBLite mobidb-lite consensus disorder prediction
40 60 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
1 289 PANTHER PTHR30168 PUTATIVE MEMBRANE PROTEIN YPFJ
1 289 InterPro IPR007343 Uncharacterised protein family, zinc metallopeptidase putative
1 287 Pfam PF04228 Putative neutral zinc metallopeptidase
1 287 InterPro IPR007343 Uncharacterised protein family, zinc metallopeptidase putative

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H1C8
AlphaFold — — full sequence — Viewing
ColabFold KP13_03827
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.948

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 33.54 0.947
2 1.19 0.01