Protein profile

KP13_03563

putative DNA-binding domain-containing protein

Genome: KpKP13

Gene: AHE43368.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVW6
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Amino acids 130
Annotations 0
Features 4
PDB binders 0
Druggability 0.615

Overview

Basic information about this protein and its source genome.

Accession
KP13_03563
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43368.1
Status
annotated
Amino acids
130
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
77.71

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.615
Structure A0A0H3GVW6
Pocket Pocket 6
P2Rank
Structure A0A0H3GVW6
Pocket No pockets
ColabFold model
FPocket 0.831 · Pocket 10
P2Rank 0.002 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 48 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
4 52 SUPERFAMILY SSF46955 Putative DNA-binding domain
4 52 InterPro IPR009061 Putative DNA-binding domain superfamily
8 128 Pfam PF07037 Putative transcription regulator (DUF1323)
8 128 InterPro IPR010749 YfeC-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVW6
AlphaFold — — full sequence — Viewing
ColabFold KP13_03563
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.615
1 0.003
2 0.0
4 0.0