Protein profile

KP13_03739

hypothetical protein

Genome: KpKP13

Gene: AHE43388.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMB9
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Amino acids 163
Annotations 0
Features 8
PDB binders 0
Druggability 0.14

Overview

Basic information about this protein and its source genome.

Accession
KP13_03739
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43388.1
Status
annotated
Amino acids
163
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
85.39

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.14
Structure A0A0H3GMB9
Pocket Pocket 13
P2Rank 0.101
Structure A0A0H3GMB9
Pocket Pocket 1
ColabFold model
FPocket 0.34 · Pocket 12
P2Rank 0.162 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 71 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
5 157 NCBIfam TIGR03358 type VI secretion system contractile sheath small subunit
5 157 InterPro IPR008312 Type VI secretion system sheath protein TssB1
1 163 PIRSF PIRSF028301 UCP028301
1 163 InterPro IPR008312 Type VI secretion system sheath protein TssB1
7 157 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2
7 157 InterPro IPR008312 Type VI secretion system sheath protein TssB1
3 160 PANTHER PTHR35850 CYTOPLASMIC PROTEIN-RELATED
3 160 InterPro IPR008312 Type VI secretion system sheath protein TssB1

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMB9
AlphaFold — — full sequence — Viewing
ColabFold KP13_03739
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.6 0.199