Protein profile

KP13_01065

hypothetical protein

Genome: KpKP13

Gene: AHE43407.1 Structure source: AlphaFold + ColabFold UniProt A0A6A8ERC0
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Amino acids 535
Annotations 0
Features 8
PDB binders 0
Druggability 0.211

Overview

Basic information about this protein and its source genome.

Accession
KP13_01065
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43407.1
Status
annotated
Amino acids
535
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
88.48

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.211
Structure A0A6A8ERC0
Pocket Pocket 8
P2Rank 0.32
Structure A0A6A8ERC0
Pocket Pocket 1
ColabFold model
FPocket 0.67 · Pocket 15
P2Rank 0.469 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 52 / 4744 genomes with a hit
Normalized 0.011

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
205 229 MobiDBLite mobidb-lite consensus disorder prediction
32 492 NCBIfam TIGR03362 type VI secretion system protein TssA
32 492 InterPro IPR017739 Type VI secretion system-associated, VCA0119
26 494 PANTHER PTHR37024 TYPE VI SECRETION SYSTEM DUF2094 AND IMPA-RELATED DOMAIN PROTEIN
37 141 Pfam PF06812 ImpA, N-terminal, type VI secretion system
37 141 InterPro IPR010657 ImpA, N-terminal
231 491 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ
231 491 InterPro IPR017739 Type VI secretion system-associated, VCA0119

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A6A8ERC0
AlphaFold — — full sequence — Viewing
ColabFold KP13_01065
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
8 0.211

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.07 0.102
2 2.79 0.086
3 2.26 0.056
4 1.39 0.017