Protein profile

KP13_01062

hypothetical protein

Genome: KpKP13

Gene: AHE43410.1 Structure source: AlphaFold + ColabFold UniProt A0A6A8ERB8
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Amino acids 174
Annotations 0
Features 16
PDB binders 0
Druggability 0.035

Overview

Basic information about this protein and its source genome.

Accession
KP13_01062
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43410.1
Status
annotated
Amino acids
174
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
85.67

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.035
Structure A0A6A8ERB8
Pocket Pocket 2
P2Rank
Structure A0A6A8ERB8
Pocket No pockets
ColabFold model
FPocket 0.064 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 45 / 4744 genomes with a hit
Normalized 0.009

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
20 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
44 164 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113
44 164 InterPro IPR017734 Type VI secretion system, lipoprotein SciN
42 174 Gene3D G3DSA:2.60.40.4150 Type VI secretion system, lipoprotein SciN
42 174 InterPro IPR038706 Type VI secretion protein SciN-like superfamily
7 150 NCBIfam TIGR03352 type VI secretion system lipoprotein TssJ
7 150 InterPro IPR017734 Type VI secretion system, lipoprotein SciN
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
1 19 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
7 164 PANTHER PTHR37625 OUTER MEMBRANE LIPOPROTEIN-RELATED
7 164 InterPro IPR017734 Type VI secretion system, lipoprotein SciN
25 174 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 21 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A6A8ERB8 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A6A8ERB8
AlphaFold — — full sequence — Viewing
ColabFold KP13_01062
ColabFold — — full sequence — Loaded