Protein profile

KP13_01044

hypothetical protein

Genome: KpKP13

Gene: AHE43428.1 Structure source: AlphaFold + ColabFold UniProt A6TC21
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Amino acids 80
Annotations 0
Features 7
PDB binders 0
Druggability 0.246

Overview

Basic information about this protein and its source genome.

Accession
KP13_01044
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43428.1
Status
annotated
Amino acids
80
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
45.0
DEG E-value
5.04e-22
Localization
Unknown
ColabFold pLDDT
86.03

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.246
Structure A6TC21
Pocket Pocket 2
P2Rank
Structure A6TC21
Pocket No pockets
ColabFold model
FPocket 0.393 · Pocket 4
P2Rank 0.039 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 113 / 4744 genomes with a hit
Normalized 0.024

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
23 43 Coils Coil Coil
1 80 PANTHER PTHR38769 UPF0381 PROTEIN YFCZ-RELATED
1 80 InterPro IPR005272 Protein of unknown function (DUF406)
9 80 Gene3D G3DSA:3.30.70.860 -
9 80 InterPro IPR035571 UPF0234-like, C-terminal
1 80 NCBIfam TIGR00743 DUF406 family protein
1 80 Pfam PF04175 Protein of unknown function (DUF406)

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A6TC21
AlphaFold — — full sequence — Viewing
ColabFold KP13_01044
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.246
5 0.208