Protein profile

KP13_00939

hypothetical protein

Genome: KpKP13

Gene: AHE43534.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GSX0

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Amino acids 97

Annotations 0

Features 7

PDB binders 0

Druggability 0.61

Overview

Basic information about this protein and its source genome.

Accession: KP13_00939
Assembly: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene: AHE43534.1
Status: annotated
Amino acids: 97
Structure source: AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Human identity (%): 0.0
Gut microbiome off-target: hit
Essential (DEG): Y
DEG identity (%): 85.333
DEG E-value: 1.4e-42
Localization: Unknown
ColabFold pLDDT: 78.54

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.61

Structure A0A0H3GSX0

Pocket Pocket 4

P2Rank

Structure A0A0H3GSX0

Pocket No pockets

ColabFold model

FPocket 0.621 · Pocket 8

Core conservation Accessory gene

Roary core

CoreCruncher accessory

Gut microbiome 135 / 4744 genomes with a hit

Normalized 0.028

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records

Show feature table

Start	End	DB	Term	Name
48	91	Pfam	PF07208	Protein of unknown function (DUF1414)
48	91	InterPro	IPR009857	Uncharacterised protein family UPF0352
23	96	SUPERFAMILY	SSF158651	YejL-like
23	96	InterPro	IPR023202	YejL-like superfamily
23	93	Hamap	MF_00816	UPF0352 protein YejL [yejL].
23	93	InterPro	IPR009857	Uncharacterised protein family UPF0352
23	97	Gene3D	G3DSA:1.10.3390.10	-

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold AF_A0A0H3GSX0	AlphaFold	—	—	full sequence	—	Viewing
ColabFold KP13_00939	ColabFold	—	—	full sequence	—	Loaded

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
8				0.326
3				0.004
1				0.0
5				0.0

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
8				0.621