Protein profile

KP13_03803

putative glycosyltransferase family 2 in cps region

Genome: KpKP13

Gene: AHE43660.1 Structure source: AlphaFold + ColabFold UniProt A0A024GWD3
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Amino acids 298
Annotations 1
Features 11
PDB binders 0
Druggability 0.012

Overview

Basic information about this protein and its source genome.

Accession
KP13_03803
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43660.1
Status
annotated
Amino acids
298
Structure source
AlphaFold + ColabFold
GO
GO:0016757 Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.22

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.012
Structure A0A024GWD3
Pocket Pocket 7
P2Rank 0.757
Structure A0A024GWD3
Pocket Pocket 1
ColabFold model
FPocket 0.025 · Pocket 4
P2Rank 0.861 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016757 Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 246 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
269 298 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
7 277 SUPERFAMILY SSF53448 Nucleotide-diphospho-sugar transferases
7 277 InterPro IPR029044 Nucleotide-diphospho-sugar transferases
247 268 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
247 269 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
2 250 PANTHER PTHR43179 RHAMNOSYLTRANSFERASE WBBL
1 218 Gene3D G3DSA:3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
1 218 InterPro IPR029044 Nucleotide-diphospho-sugar transferases
7 172 Pfam PF00535 Glycosyl transferase family 2
7 172 InterPro IPR001173 Glycosyltransferase 2-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A024GWD3
AlphaFold — — full sequence — Viewing
ColabFold KP13_03803
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 12.04 0.636
2 8.79 0.47
3 3.48 0.127
4 2.2 0.053