Protein profile

KP13_04759

tellurite resistance YeaR-type protein

Genome: KpKP13

Gene: AHE43722.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVQ4
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Amino acids 110
Annotations 0
Features 8
PDB binders 0
Druggability 0.513

Overview

Basic information about this protein and its source genome.

Accession
KP13_04759
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43722.1
Status
annotated
Amino acids
110
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
95.42

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.513
Structure A0A0H3GVQ4
Pocket Pocket 1
P2Rank 0.589
Structure A0A0H3GVQ4
Pocket Pocket 1
ColabFold model
FPocket 0.576 · Pocket 1
P2Rank 0.737 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 66 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
4 108 SUPERFAMILY SSF51197 Clavaminate synthase-like
3 107 PIRSF PIRSF020632 YeaR
3 107 InterPro IPR014510 Tellurite resistance predicted, YeaR
3 109 Gene3D G3DSA:2.60.120.10 Jelly Rolls
3 109 InterPro IPR014710 RmlC-like jelly roll fold
14 98 Pfam PF09313 Domain of unknown function (DUF1971)
14 98 InterPro IPR015392 Domain of unknown function DUF1971
108 110 Coils Coil Coil

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVQ4
AlphaFold — — full sequence — Viewing
ColabFold KP13_04759
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.513
3 0.004
5 0.004
2 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 13.03 0.589
2 1.28 0.011